What is Vicodin? Acetaminophen and hydrocodone are both present in Vicodin. A common opioid painkiller is hydrocodone. A narcotic is another name for an opioid. Hydrocodone's effects are enhanced with acetaminophen, a less effective painkiller. Tablets of Vicodin are used to treat mild to moderately severe pain. Other uses for Vicodin that aren't covered in this pharmaceutical guide are possible. Warnings Breathing can be slowed or stopped by hydrocodone. Never take this medication in bigger or longer amounts than recommended. Even in low doses, narcotic painkillers have the potential to develop a dependence. Never give Vicodin to someone else, particularly if they have a history of drug abuse or addiction. The drug should be kept out of the reach of others. If you have taken an MAO inhibitor during the previous 14 days, such as phenelzine, isocarboxazid, linezolid, methylene blue injection, rasagiline, selegiline, or tranylcypromine, you should avoid using Vicodin. Vicodin shouldn't be taken in excess of what is advised. Acetaminophen overdoses might harm your liver or result in death. If you have nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored feces, or jaundice, call your doctor right once (yellowing of your skin or eyes) If you have skin redness or a rash that spreads and results in blistering and peeling, stop taking Vicodin and contact your doctor right once. Earlier than using this medication If you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications, or if you are allergic to acetaminophen (Tylenol) or hydrocodone, you should avoid using Vicodin. If you have used an MAO inhibitor within the last 14 days, avoid using this medication. There may be a harmful medication interaction. Isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine are examples of MAO inhibitors. A dangerous disease known as serotonin syndrome can be brought on by certain medications and hydrocodone interaction. If you also take medication for Parkinson's disease, depression, mental illness, migraines, severe infections, or to avoid nausea and vomiting, let your doctor know. Before changing the way or time you take your drugs, consult your doctor. Vicodin shouldn't be taken if you have: severe respiratory difficulties or asthma; or An obstruction in your intestines or stomach. Inform your doctor of any of the following to ensure Vicodin is safe for you: Respiratory issues, sleep apnea (when breathing is interrupted while sleeping); liver illness A dependency on drugs or alcohol; Renal illness; A concussion or convulsions; Issues with urinating; or Issues with your pancreas, gallbladder, or thyroid.